Repositorio Ciencia Abierta Universidad del Bío-Bío

El presente artículo busca conocer la vivencia de una familia de orientación homosexual en función de las competencias parentales que estas desarrollan en la crianza de su hija. La investigación es de tipo cualitativa, la producción de datos se realiza mediante entrevistas semiestructuradas y la entrega de autorregistros; el análisis de los datos se desarrolla bajo el análisis de contenido. Los resultados del estudio arrojan una vivencia positiva de las madres en función de la crianza de su hija, en donde han priorizado trabajar y potenciar el vínculo con ella, enraizando valores, normas y limites que permitiría un desarrollo óptimo en base a los buenos tratos dentro del proceso de su crianza.

EL ARTÍCULO INVESTIGA LA CONVERGENCIA ENTRE REDES SOCIALES Y TELEVISIÓN ANALIZANDO LA RECEPCIÓN EN INSTAGRAM DE LA SERIE «POMBO». COMPARANDO LAS CUENTAS DE LA INFLUENCER MARÍA POMBO Y LA PLATAFORMA PRIME VIDEO ESPAÑA MEDIANTE MÉTODOS MIXTOS (ENGAGEMENT, SENTIMIENTO, LINGÜÍSTICO-COMPUTACIONAL, CUALITATIVO) SE ENCONTRARON DIFERENCIAS SIGNIFICATIVAS. LA CUENTA DE LA INFLUENCER GENERA MAYOR INTERACCIÓN Y RESPUESTA POSITIVA, VINCULADA A PERCEPCIONES DE AUTENTICIDAD Y CONTINUIDAD TRANSMEDIA. LA CUENTA DE STREAMING (PRIME VIDEO ESPAÑA) MOSTRÓ MÁS ESCEPTICISMO Y UN ENFOQUE EN EL SERVICIO. LA AUTENTICIDAD PERCIBIDA DEL EMISOR RESULTA CRUCIAL PARA EL ÉXITO DE ESTAS ESTRATEGIAS DE EXPANSIÓN DE MARCA PERSONAL A NUEVOS MEDIOS.

THIS STUDY PROPOSES TWO OPTIMIZATION MODELS AND A COLUMN-GENERATION ALGORITHM, APPLIED AT THE ROOT NODE, TO SUPPORT TACTICAL PLANNING IN SAWMILLS BY DYNAMICALLY GENERATING LOG CUTTING PATTERNS ALIGNED WITH SUSTAINABILITY AND EFFICIENCY OBJECTIVES. STARTING FROM AN INDUSTRIAL DATASET CONTAINING 160 CUTTING PATTERNS, THE METHODOLOGY ITERATIVELY INCORPORATES NEW GEOMETRICALLY FEASIBLE CONFIGURATIONS GUIDED BY THE DUAL PRICES OF A PRIMARY MODEL, EXPLICITLY CONSIDERING LOG SUPPLY, PRODUCT DEMAND, AND ALTERNATIVE TACTICAL CRITERIA. THREE COMPUTATIONAL EXPERIMENTS WERE CONDUCTED. THE FIRST ASSESSES THE CONVERGENCE BEHAVIOR OF THE ALGORITHM AND SHOWS REDUCTIONS IN TOTAL LOG CONSUMPTION OF UP TO 31% AS NEW PATTERNS ARE GENERATED. THE SECOND DEMONSTRATES THAT STRATEGIES AIMED AT MINIMIZING LOG USAGE AND RESIDUES CAN ACHIEVE NEAR-OPTIMAL SOLUTIONS WITH ONLY 20-25 PATTERNS, SINCE ADDITIONAL CONFIGURATIONS PROVIDE MARGINAL IMPROVEMENTS WHILE INCREASING SETUP TIME AND OPERATIONAL COMPLEXITY. THE THIRD EXPERIMENT CONFIRMS THAT NEAR-OPTIMAL PERFORMANCE CAN BE REACHED WITH A MODERATE NUMBER OF ACTIVE PATTERNS, FACILITATING PRACTICAL IMPLEMENTATION IN INDUSTRIAL SETTINGS. OVERALL, THE PROPOSED METHODOLOGY OFFERS A FLEXIBLE AND SUSTAINABILITY-ORIENTED DECISION-SUPPORT TOOL FOR SAWMILL TACTICAL PLANNING, IMPROVING RAW-MATERIAL UTILIZATION, REDUCING RESIDUES, AND ENHANCING ALIGNMENT BETWEEN SUPPLY AND DEMAND WHILE MAINTAINING OPERATIONAL FEASIBILITY.

DYSFERLINOPATHIES ARE PROGRESSIVE MUSCULAR DYSTROPHIES CAUSED BY DYSF MUTATIONS, LEADING TO IMPAIRED MEMBRANE REPAIR, CHRONIC INFLAMMATION, LIPID ACCUMULATION, AND MUSCLE DEGENERATION. NO APPROVED THERAPIES CURRENTLY HALT THE PROGRESSION OF THIS DISEASE. HERE, WE EVALUATED THE EFFECTS OF DAILY ORAL ADMINISTRATION OF PULVERIZED BOLDO (PEUMUS BOLDUS) LEAVES, COMMONLY USED AS A NUTRACEUTICAL, TO BLAJ MICE, A MODEL OF DYSFERLINOPATHY. SYMPTOMATIC BIAJ MICE WERE TREATED FOR FOUR WEEKS WITH BOLDO AND PRESENTED SIGNIFICANTLY IMPROVED GRIP STRENGTH AND RESTORED ENDOTHELIAL-DEPENDENT VASODILATION. MUSCLE PERFUSION AND CAPILLARY DENSITY IN THE GASTROCNEMIUS WERE BOTH ENHANCED BY TREATMENT. HISTOLOGICAL ANALYSES REVEALED THAT BOLDO PREVENTED MYOFIBER ATROPHY, REDUCED CENTRALLY NUCLEATED FIBERS, AND IMPROVED MUSCLE TISSUE ARCHITECTURE. LIPID ACCUMULATION OBSERVED IN BLAJ MUSCLES WAS ABSENT IN BOLDO-TREATED MICE. AT THE CELLULAR LEVEL, BOLDO NORMALIZED SARCOLEMMA MEMBRANE PERMEABILITY (DYE UPTAKE) AND REDUCED MRNA LEVELS OF INFLAMMASOME COMPONENTS (NLRP3, ASC, AND IL-1?), SUGGESTING ANTI-INFLAMMATORY ACTIVITY. THESE FINDINGS INDICATE THAT BOLDO IMPROVES VASCULAR AND MUSCLE INTEGRITY, SUPPORTING ITS POTENTIAL AS A COMPLEMENTARY THERAPEUTIC STRATEGY FOR DYSFERLINOPATHY.