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CHEMICAL ANALYSIS AND IN VITRO BIOACTIVITY OF ESSENTIAL OIL OF LAURELIA SEMPERVIRENS AND SAFROLE DERIVATIVES AGAINST OOMYCETE FISH PATHOGENS

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dc.creatorENRIQUE ADALBERTO WERNER NAVARRETE
dc.date2021
dc.date.accessioned2025-01-10T15:23:34Z
dc.date.available2025-01-10T15:23:34Z
dc.date.issued2021
dc.description.abstractIN THIS STUDY, THE ESSENTIAL OIL (EO) FROM LAURELIA SEMPERVIRENS WAS ANALYZED BY GC/MS AND SAFROLE (1) WAS IDENTIFIED AS THE MAJOR METABOLITE 1, WAS SUBJECTED TO DIRECT REACTIONS ON THE OXYGENATED GROUPS IN THE AROMATIC RING AND IN THE SIDE CHAIN, AND EIGHT COMPOUNDS (4 TO 12) WERE OBTAINED BY THE PROCESS. EO AND COMPOUNDS 4-12 WERE SUBJECTED TO BIOLOGICAL ASSAYS ON 24 STRAINS OF THE GENUS SAPROLEGNIA, SPECIFICALLY OF THE SPECIES 12 S. PARASITICA AND 12 S. AUSTRALIS. EO SHOWED A SIGNIFICANT EFFECT AGAINST SAPROLEGNIA STRAINS. COMPOUND 6 PRESENTS THE HIGHEST ACTIVITY AGAINST TWO RESISTANT STRAINS, WITH MINIMUM INHIBITORY CONCENTRATION (MIC) AND MINIMUM OOMYCETICIDAL CONCENTRATION (MOC) VALUES OF 25 TO 100 AND 75 TO 125 ?G/ML, RESPECTIVELY. THE RESULTS SHOW THAT COMPOUND 6 EXHIBITED SUPERIOR ACTIVITIES COMPARED TO THE COMMERCIAL CONTROLS BRONOPOL AND AZOXYSTROBIN USED TO COMBAT THESE PATHOGENS.
dc.formatapplication/pdf
dc.identifier.doi10.3390/molecules26216551
dc.identifier.issn1420-3049
dc.identifier.issn1420-3049
dc.identifier.urihttps://repositorio.ubiobio.cl/handle/123456789/11798
dc.languagespa
dc.publisherMOLECULES
dc.relation.uri10.3390/molecules26216551
dc.rightsPUBLICADA
dc.titleCHEMICAL ANALYSIS AND IN VITRO BIOACTIVITY OF ESSENTIAL OIL OF LAURELIA SEMPERVIRENS AND SAFROLE DERIVATIVES AGAINST OOMYCETE FISH PATHOGENS
dc.typeARTÍCULO
dspace.entity.typePublication
ubb.EstadoPUBLICADA
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.SedeCHILLÁN
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