Publicación:
BRAIN VASCULAR DYSFUNCTION IN MOTHERS AND THEIR CHILDREN EXPOSED TO PREECLAMPSIA

Vista sencilla de ítem
dc.creatorBELÉN OCTAVIA DE LOS ÁNGELES IBÁÑEZ JARA
dc.creatorFELIPE ANDRÉS TRONCOSO BASSO
dc.creatorHERMES SEBASTIÁN SANDOVAL RIVAS
dc.creatorCARLOS ALONSO ESCUDERO OROZCO
dc.date2023
dc.date.accessioned2025-01-10T15:45:39Z
dc.date.available2025-01-10T15:45:39Z
dc.date.issued2023
dc.description.abstractPREECLAMPSIA IS A MATERNAL SYNDROME CHARACTERIZED BY THE NEW ONSET OF HYPERTENSION AND PROTEINURIA AFTER 20 WEEKS OF GESTATION ASSOCIATED WITH MULTISYSTEMIC COMPLICATIONS, INCLUDING BRAIN ALTERATIONS. INDEED, BRAIN COMPLICATIONS ASSOCIATED WITH PREECLAMPSIA ARE THE LEADING DIRECT CAUSES OF FETAL AND MATERNAL MORBIDITY AND MORTALITY, ESPECIALLY IN LOW- AND MIDDLE-INCOME COUNTRIES. IN ADDITION TO THE WELL-RECOGNIZED LONG-TERM ADVERSE CARDIOVASCULAR EFFECTS OF PREECLAMPSIA, WOMEN WHO HAVE HAD PREECLAMPSIA HAVE HIGHER RISK OF STROKE, DEMENTIA, INTRACEREBRAL WHITE MATTER LESIONS, EPILEPSY, AND PERHAPS ALSO COGNITIVE DECLINE POSTPARTUM. FURTHERMORE, INCREASING EVIDENCE HAS ALSO ASSOCIATED PREECLAMPSIA WITH SIMILAR COGNITIVE AND CEREBRAL DISORDERS IN THE OFFSPRING. HOWEVER, THE MECHANISTIC LINKS BETWEEN THESE ASSOCIATIONS REMAIN UNRESOLVED. THIS ARTICLE SUMMARIZES THE CURRENT KNOWLEDGE ABOUT THE CEREBROVASCULAR COMPLICATIONS ELICITED BY PREECLAMPSIA AND THE POTENTIAL PATHOPHYSIOLOGICAL MECHANISMS INVOLVED, EMPHASIZING THE IMPAIRED BRAIN VASCULAR FUNCTION IN THE MOTHER AND THEIR OFFSPRING.
dc.formatapplication/pdf
dc.identifier.doi10.1161/HYPERTENSIONAHA.122.19408
dc.identifier.issn1524-4563
dc.identifier.issn0194-911X
dc.identifier.urihttps://repositorio.ubiobio.cl/handle/123456789/13532
dc.languagespa
dc.publisherHYPERTENSION
dc.relation.uri10.1161/HYPERTENSIONAHA.122.19408
dc.rightsPUBLICADA
dc.subjectpregnancy
dc.subjectpreeclampsia
dc.subjectcognition
dc.subjectbrain
dc.subjectblood-brain barrier
dc.titleBRAIN VASCULAR DYSFUNCTION IN MOTHERS AND THEIR CHILDREN EXPOSED TO PREECLAMPSIA
dc.typeARTÍCULO DE REVISIÓN
dspace.entity.typePublication
ubb.EstadoPUBLICADA
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.SedeCHILLÁN
ubb.SedeCHILLÁN
ubb.SedeCHILLÁN
ubb.SedeCHILLÁN
Archivos
Colecciones
Otros Documentos