Publicación: A BIOINFORMATIC APPROACH TO IDENTIFY CONFIRMED AND PROBABLE CRISPR-CAS SYSTEMS IN THE ACINETOBACTER CALCOACETICUS-ACINETOBACTER BAUMANNII COMPLEX GENOMES
Fecha
2024
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Frontiers in Microbiology
Resumen
THE ACINETOBACTER CALCOACETICUS?ACINETOBACTER BAUMANNII
COMPLEX, OR ACB COMPLEX, CONSISTS OF SIX SPECIES: ACINETOBACTER BAUMANNII, ACINETOBACTER CALCOACETICUS, ACINETOBACTER NOSOCOMIALIS, ACINETOBACTER PITTII, ACINETOBACTER SEIFERTII, AND ACINETOBACTER LACTUCAE. A. BAUMANNII IS THE MOST CLINICALLY SIGNIFICANT OF THESE SPECIES AND IS FREQUENTLY RELATED TO HEALTHCARE-ASSOCIATED INFECTIONS (HCAIS). CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT (CRISPR) ARRAYS AND ASSOCIATED GENES (CAS) CONSTITUTE BACTERIAL ADAPTIVE IMMUNE SYSTEMS AND FUNCTION AS VARIABLE GENETIC ELEMENTS. THIS STUDY AIMED TO CONDUCT A GENOMIC ANALYSIS OF ACB COMPLEX GENOMES AVAILABLE IN DATABASES TO DESCRIBE AND CHARACTERIZE CRISPR SYSTEMS AND CAS GENES.
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prophages, CRISPR systems, cas genes, Acinetobacter calcoaceticus?Acinetobacter baumannii complex, Acinetobacter baumannii
