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BACTERICIDES PROPERTIES OF CHITOSAN METAL QUANTUM DOTS MICROBIAL PATHOGENICITY AGAINST E. COLI, S. AUREUS, AND S. TYPHI

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dc.creatorGALO CÁRDENAS TRIVIÑO
dc.date2020
dc.date.accessioned2025-01-10T15:15:57Z
dc.date.available2025-01-10T15:15:57Z
dc.date.issued2020
dc.description.abstractTHE NANOTECHNOLOGY IS CONSIDERED AS A TOOL TO OVERCOME ANTIBIOTIC-RESISTANT INFECTIONS. THE AIM OF THIS STUDY WAS TO INVESTIGATE THE ANTIBACTERIAL PROPERTIES OF QUANTUM DOTS (QDS) OF AU, AG, AND CU SUPPORTED IN CHITOSAN AGAINSTESCHERICHIA COLI(ATCC 25922),STAPHYLOCOCCUS AUREUS(ATCC 29213), ANDSALMONELLA TYPHI(ATCC 9993) STRAINS. THE QDS WERE SYNTHESIZED BY THE METHOD (CHEMICAL LIQUID DEPOSITION, CLD) USING 2-ETHOXYETHANOL AS SOLVENT (1X10-3 MAPPROXIMATE DISPERSION CONCENTRATION). THEN, NPS SUPPORTED IN CHITOSAN WERE SYNTHESIZED BY SOLVATED METAL ATOM DISPERSION (SMAD) IN TWO CONCENTRATIONS, LABELLED [A] AND [B] (0.05 AND 0.1 G/L) FOR EACH METAL WITH CHITOSAN RESULTING IN AN AVERAGE SIZE OF AU10 +/- 2.0, AG6 +/- 1.3, AND CU10 +/- 2.4 NM, RESPECTIVELY. SEVERAL OTHER TECHNIQUES WERE PERFORMED SUCH AS TEM, SEM/EDX, TGA, DSC, AND FT-IR FOR CHARACTERIZING QDS. THE ANTIBACTERIAL ASSAY WAS PERFORMED WITH 8 AGENTS ON CULTURES OFE. COLI,S. AUREUS, ANDS. TYPHIBY DISK DIFFUSION, BROTH MACRODILUTION, AND DETERMINING DEATH CURVE TO THE MOST SENSITIVE PATHOGEN. THE ANTIBACTERIAL EFFECT OF THE NANOPARTICLES WAS COMPARED USING THE DIAMETER OF GROWTH INHIBITION ZONE BY AGAR DISK DIFFUSION AND THROUGH THE MINIMAL INHIBITORY CONCENTRATION (MIC) AND MINIMAL BACTERICIDE CONCENTRATION (MBC) OBTAINED BY MACRODILUTION IN BATCH CULTURE WITH AN INITIAL INOCULUM OF 5X10(5) CFU/ML. THE HIGHEST BACTERICIDAL EFFECT WAS OBTAINED WITH NANOPARTICLES OF AU, AG, AND CU (0.1 G/L) WITH MIC AND MBC OF 200 AND 400 MG/ML, RESPECTIVELY. THE GREATEST BACTERICIDAL EFFECT CONSIDERING THE THREE PATHOGENS TURNED OUT TO BE AG QDS (0.05 AND 0.1 G/L). A BACTERICIDAL EFFECT OF METAL NANOPARTICLES IS AFFECTED MAINLY BY THE ELECTRONEGATIVITY, THE CONCENTRATION OF NANOPARTICLES, AND THE BACTERIAL AGE CULTURE.
dc.formatapplication/pdf
dc.identifier.doi10.1155/2020/5920941
dc.identifier.issn1687-9430
dc.identifier.issn1687-9422
dc.identifier.urihttps://repositorio.ubiobio.cl/handle/123456789/11195
dc.languagespa
dc.publisherInternational Journal of Polymer Science
dc.relation.uri10.1155/2020/5920941
dc.rightsPUBLICADA
dc.titleBACTERICIDES PROPERTIES OF CHITOSAN METAL QUANTUM DOTS MICROBIAL PATHOGENICITY AGAINST E. COLI, S. AUREUS, AND S. TYPHI
dc.title.alternativeBACTERICIDAS PROPIEDADES DEL METAL DE QUITOSANO PUNTOS CUÁNTICOS PATOGENICIDAD MICROBIANA CONTRA E. COLI, S. AUREUS Y S. TYPHI
dc.typeARTÍCULO
dspace.entity.typePublication
ubb.EstadoPUBLICADA
ubb.Otra ReparticionDEPARTAMENTO DE INGENIERIA EN MADERAS
ubb.SedeCONCEPCIÓN
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