Publicación: ANTIFUNGAL ACTIVITIES OF SECONDARY METABOLITES ISOLATED FROM LIQUID FERMENTATIONS OF STEREUM HIRSUTUM (SH134-11)AGAINST BOTRYTIS CINEREA (GREY MOULD AGENT)
| dc.creator | CARLOS LEONARDO ARMANDO CÉSPEDES ACUÑA | |
| dc.date | 2017 | |
| dc.date.accessioned | 2025-01-10T14:55:02Z | |
| dc.date.available | 2025-01-10T14:55:02Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | EXTRACTS OBTAINED FROM LIQUID MYCELIAL FERMENTATIONS OF THE CHILEAN FUNGUS STEREUM HIRSUTUM (SH134-11) SHOWED ANTIFUNGAL ACTIVITY AGAINST BOTRYTIS CINEREA. TWO TYPES OF EXTRACTS WERE OBTAINED: ETOAC-EXTRACT (LIQUID PHASE) AND MEOH-EXTRACT (MYCELIAL PHASE). PLATE DIFFUSION ASSAY SHOWED THAT ETOAC-EXTRACTS WERE MORE ACTIVE THAN MEOH-EXTRACTS. A LARGE-SCALE FERMENTATION OF SH134-11 AND CHROMATOGRAPHIC METHODS ALLOWED TO ISOLATED FOUR COMPOUNDS: MS-3, VIBRALACTONE, VIBRALACTONE B AND STERENIN D. ONLY STERENIN D SHOWED ANTIFUNGAL ACTIVITY AGAINST B. CINEREA IN THE TESTS PERFORMED. EFFECTS ON THE MYCELIAL GROWTH OF B. CINEREA SHOWED THAT STERENIN D SHOWED INHIBITION AT 1000-2000 ?G/ML REACHING 67% AND 76% RESPECTIVELY. STERENIN D WAS MORE EFFECTIVE TO CONTROL THE SPOROGENESIS, INHIBITING IN 96% THE SPORULATION AT 500 ?G/ML. ASSAYS SHOWED THAT STERENIN D EXHIBITED A MINIMAL FUNGICIDAL CONCENTRATION (MFC) OF 50 ?G/ML AND MINIMAL INHIBITORY CONCENTRATION (MIC) AT 20 ?G/ML. OUR STUDY INDICATED THAT SUBMERGED FERMENTATIONS OF CHILEAN S. HIRSUTUM (SH134-11) PRODUCED EXTRACTS WITH ANTIFUNGAL ACTIVITY AND STERENIN D IS RESPONSIBLE FOR THIS ACTIVITY, WHICH COULD BE USED AS POSSIBLE BIOFUNGICIDES ALTERNATIVE TO SYNTHETIC FUNGICIDES. | |
| dc.format | application/pdf | |
| dc.identifier.doi | 10.1016/j.fct.2017.05.036 | |
| dc.identifier.issn | 1873-6351 | |
| dc.identifier.issn | 0278-6915 | |
| dc.identifier.uri | https://repositorio.ubiobio.cl/handle/123456789/9543 | |
| dc.language | spa | |
| dc.publisher | FOOD AND CHEMICAL TOXICOLOGY | |
| dc.relation.uri | 10.1016/j.fct.2017.05.036 | |
| dc.rights | PUBLICADA | |
| dc.title | ANTIFUNGAL ACTIVITIES OF SECONDARY METABOLITES ISOLATED FROM LIQUID FERMENTATIONS OF STEREUM HIRSUTUM (SH134-11)AGAINST BOTRYTIS CINEREA (GREY MOULD AGENT) | |
| dc.type | ARTÍCULO | |
| dspace.entity.type | Publication | |
| ubb.Estado | PUBLICADA | |
| ubb.Otra Reparticion | DEPARTAMENTO DE CIENCIAS BASICAS | |
| ubb.Sede | CHILLÁN |
