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INSECTICIDAL, ANTIFEEDANT AND ACETYLCHOLINESTERASE INHIBITORY ACTIVITY OF SESQUITERPENOIDS DERIVED FROM EUDESMANE, THEIR MOLECULAR DOCKING AND QSAR

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dc.creatorSOLEDAD MARGARITA QUIROZ CARREÑO
dc.creatorEDGAR RAFAEL PASTENE NAVARRETE
dc.creatorCARLOS LEONARDO ARMANDO CÉSPEDES ACUÑA
dc.creatorJULIO ENRIQUE ILDEFONSO ALARCÓN ENOS
dc.date2024
dc.date.accessioned2025-01-10T15:50:05Z
dc.date.available2025-01-10T15:50:05Z
dc.date.issued2024
dc.description.abstractTHIS WORK EVALUATED THE INSECTICIDAL, ANTIFEEDANT AND ACHE INHIBITORY ACTIVITY OF COMPOUNDS WITH EUDESMANE SKELETON. THE INSECTICIDAL ACTIVITY WAS TESTED AGAINST LARVAE OF DROSOPHILA MELANOGASTER AND CYDIA POMONELLA, THE COMPOUNDS 3 AND 4 WERE THE MOST ACTIVE (LC50 OF 104.2 AND 106.7 ?M; 82.0 AND 84.4 ?M, RESPECTIVELY). LIKEWISE, THE MENTIONED COMPOUNDS WERE THOSE THAT SHOWED THE HIGHEST ACETYLCHOLINESTERASE INHIBITORY ACTIVITY, WITH IC50 OF 0.26 ± 0.016 AND 0.77 ± 0.016 ?M, RESPECTIVELY.
dc.formatapplication/pdf
dc.identifier.doi10.1016/j.pestbp.2024.105841
dc.identifier.issn1095-9939
dc.identifier.issn0048-3575
dc.identifier.urihttps://repositorio.ubiobio.cl/handle/123456789/13870
dc.languagespa
dc.publisherPESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
dc.relation.uri10.1016/j.pestbp.2024.105841
dc.rightsPUBLICADA
dc.subjectQSAR
dc.subjectInsecticidal activity
dc.subjectEudesmanolides
dc.subjectDihydroagarofurans
dc.subjectAntifeedant activity
dc.subjectAChE
dc.titleINSECTICIDAL, ANTIFEEDANT AND ACETYLCHOLINESTERASE INHIBITORY ACTIVITY OF SESQUITERPENOIDS DERIVED FROM EUDESMANE, THEIR MOLECULAR DOCKING AND QSAR
dc.typeARTÍCULO
dspace.entity.typePublication
ubb.EstadoPUBLICADA
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.SedeCHILLÁN
ubb.SedeCHILLÁN
ubb.SedeCHILLÁN
ubb.SedeCHILLÁN
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