Publicación:
MECHANICAL PROPERTIES OF BILAYERS CONTAINING SPERM SPHINGOMYELINS AND CERAMIDES WITH VERY LONG-CHAIN POLYUNSATURATED FATTY ACIDS

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dc.creatorHERNÁN RAÚL AHUMADA GUTIÉRREZ
dc.date2019
dc.date.accessioned2025-01-10T15:11:54Z
dc.date.available2025-01-10T15:11:54Z
dc.date.issued2019
dc.description.abstractSPHINGOMYELINS (SM) AND CERAMIDES (CER) WITH VERY LONG CHAIN POLYUNSATURATED FATTY ACIDS (V) ARE IMPORTANT COMPONENTS OF SPERMATOZOA MEMBRANES. IN THIS STUDY, THE MECHANICAL PROPERTIES OF BILAYERS OF SM AND CER WITH NONHYDROXY (N-V) AND 2-HYDROXY (H-V) FATTY ACID (30:5) WERE STUDIED BY MOLECULAR DYNAMICS SIMULATION AT DIFFERENT TEMPERATURES AND IN THE PRESENCE AND THE ABSENCE OF SALT. FROM OUR RESULTS, IT WAS EVIDENCED HOW N-V SM AND H-V SM BILAYERS SHOWED SIMILAR BEHAVIOR. WHEN N-V CER WAS ADDED TO A H-V SM BILAYER, THE GAUSSIAN CURVATURE MODULUS AND E-CURVE OF BINARY BILAYERS DECREASED. THIS VARIATION IN THE MECHANICAL PROPERTIES OF THE BILAYER CAN BE ASSOCIATED WITH AN INCIPIENT STEP DURING THE FECUNDATION PROCESS.
dc.formatapplication/pdf
dc.identifier.doi10.1016/j.chemphyslip.2018.12.008
dc.identifier.issn1873-2941
dc.identifier.issn0009-3084
dc.identifier.urihttps://repositorio.ubiobio.cl/handle/123456789/10878
dc.languagespa
dc.publisherCHEMISTRY AND PHYSICS OF LIPIDS
dc.relation.uri10.1016/j.chemphyslip.2018.12.008
dc.rightsPUBLICADA
dc.titleMECHANICAL PROPERTIES OF BILAYERS CONTAINING SPERM SPHINGOMYELINS AND CERAMIDES WITH VERY LONG-CHAIN POLYUNSATURATED FATTY ACIDS
dc.title.alternativePROPIEDADES MECÁNICAS DE LAS BICAPAS QUE CONTIENEN ESFINGOMIELINAS Y CERAMIDAS DE ESPERMATOZOIDES CON ÁCIDOS GRASOS POLIINSATURADOS DE CADENA MUY LARGA
dc.typeARTÍCULO
dspace.entity.typePublication
ubb.EstadoPUBLICADA
ubb.Otra ReparticionDEPARTAMENTO DE CIENCIAS BASICAS
ubb.SedeCHILLÁN
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