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BIOPSYCHOSOCIAL PERSPECTIVES ON HEALTHY BRAIN AGING: A NARRATIVE REVIEW

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dc.date2025
dc.date.accessioned2025-10-20T14:02:41Z
dc.date.available2025-10-20T14:02:41Z
dc.date.issued2025
dc.description.abstractTHE GLOBAL RISE IN THE ELDERLY POPULATION INHERENTLY ESCALATES THE DEMAND FOR HEALTH AND SOCIAL CARE. ENSURING COGNITIVE PERFORMANCE FOR HEALTHY BRAIN AGING PRESENTS SIGNIFICANT CHALLENGES FOR RESEARCHERS AND HEALTH PROFESSIONALS PROMOTING SELF-CARE BEHAVIORS. THIS ARTICLE AIMS TO PROVIDE A COMPREHENSIVE AND CRITICAL ANALYSIS OF THE LATEST RESEARCH ON HEALTHY BRAIN AGING BY EMPLOYING A BIOPSYCHOSOCIAL FRAMEWORK. IT INTEGRATES BIOLOGICAL, PSYCHOLOGICAL, AND SOCIAL DIMENSIONS TO ELUCIDATE THEIR COLLECTIVE INFLUENCE ON COGNITIVE HEALTH IN OLDER ADULTS. METHODOLOGICALLY, THIS ARTICLE PROVIDES A NARRATIVE REVIEW OF THE EXISTING LITERATURE. A DIVERSE ARRAY OF BIBLIOGRAPHIC RESOURCES WAS OBTAINED FROM PROMINENT ELECTRONIC DATABASES, INCLUDING MEDLINE, PUBMED, SCOPUS AND WEB OF SCIENCE, TO ENSURE BROAD COVERAGE OF THE TOPIC. THE SEARCH WAS DESIGNED TO CAPTURE RELEVANT STUDIES PUBLISHED BETWEEN 2010 AND 2025, USING KEY TERMS SUCH AS ?AGING?, ?BIOMARKER?, ?NEURODEGENERATION?, AND ?COGNITIVE PERFORMANCE?. FOLLOWING A RIGOROUS SELECTION PROCESS, TWO FIELD SPECIALISTS EVALUATED A TOTAL OF 106 FULL-TEXT ARTICLES TO IDENTIFY THOSE THAT MET THE ELIGIBILITY CRITERIA, ULTIMATELY YIELDING 70 RELEVANT STUDIES. THE FINDINGS REVEAL IMPORTANT CONNECTIONS BETWEEN PSYCHOSOCIAL AND BIOLOGICAL BIOMARKERS AND BRAIN MORPHOLOGY, HIGHLIGHTING LIFESTYLE FACTORS?SUCH AS DIET, EXERCISE, AND SOCIAL ENGAGEMENT?AS CRUCIAL FOR COGNITIVE HEALTH. THE ARTICLE ALSO UNDERSCORES SPECIFIC BIOMARKERS RELEVANT FOR ASSESSING BRAIN AGE AND THEIR RELATIONSHIP TO NEURODEGENERATIVE DISORDERS. NOTABLY, WHILE BIOLOGICAL MARKERS LIKE A?, TAU, AND ?-SYNUCLEIN (PROTEINS THAT DEFINE THE CORE MOLECULAR PATHOLOGY OF COMMON NEURODEGENERATIVE DISEASES) ARE PRESENT, THEY DO NOT GUARANTEE THE ONSET OF NEURODEGENERATIVE DISEASES; PSYCHOSOCIAL FACTORS PLAY AN ESSENTIAL ROLE IN DETERMINING DISEASE MANIFESTATION.
dc.formatapplication/pdf
dc.identifier.doi10.3390/jal5040044
dc.identifier.issn2673-9259
dc.identifier.urihttps://repositorio.ubiobio.cl/handle/123456789/14266
dc.language
dc.publisherJOURNAL OF AGEING AND LONGEVITY
dc.relation.uri10.3390/jal5040044
dc.rightsOPEN ACCESS
dc.subjectquality life
dc.subjectcognitive health
dc.subjectbrain aging
dc.subjectpsychosocial factors
dc.subjectbiological factors
dc.subjectaging
dc.titleBIOPSYCHOSOCIAL PERSPECTIVES ON HEALTHY BRAIN AGING: A NARRATIVE REVIEW
dc.typeARTÍCULO DE REVISIÓN
dspace.entity.typePublication
oaire.licenseConditionCC BY 4.0
ubb.EstadoPUBLICADA
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